The Arizona Cardinals have a lengthy injury report ahead of Week 11, with seven players officially ruled out against the San Francisco 49ers.

The Arizona Cardinals thankfully concluded their practice week on Friday in preparation for Sunday’s game against the San Francisco 49ers. Afterward, the team distributed a massive injury report that lists seven players out and six questionable.

GLENDALE, Ariz. – Linebacker Tatum Bethune quickly nixed any comparisons between Arizona Cardinals tight end Trey McBride and 49ers counterpart George Kittle. “Nah, nah, not at all. George, nobody is similar to George,” Bethune said. “George is a unicorn.”

Throughout his career, Michael Wilson has operated as the Arizona Cardinals' second receiver. This week, he has a chance to step into the top role.

Why Gannon Should Stay: Gannon's done an incredible job of establishing a brand new culture in Arizona, and he clearly has the locker room bought into him. The Cardinals, up until last week, were arguably a few plays away from being a 6-1 or 5-2 football team. Though that final gear hasn't been hit, it's clear there's potential to work with.

ESPN and NFL Media are both reporting the Cardinals are likely to part ways with quarterback Kyler Murray, as Jacoby Bissett takes over as starter.

Unless something changes, the Cardinals and Kyler Murray appear headed for a split, opening the door for Arizona to draft a QB in 2026.

The San Francisco 49ers released their latest injury updates headed into the Week 11 contest versus the Arizona Cardinals.