In human cells, lengthy strands of DNA have to be carefully organized and compacted so they'll fit into the nucleus; our genome is arranged into chromosomes that have to be duplicated each time a cell ...

Female mammals carry two X chromosomes, while male mammals carry an X and a Y chromosome. The X chromosome carries a thousand genes, so in females, one of the X chromosomes must be silenced to avoid ...

During the development of gametes, such as egg and sperm cells in humans, chromosomes are broken and rearranged at many positions. Using state of the art technology, researchers in Austria have ...

Here, we discuss the recently proposed oncogene-induced mitotic stress model that provides a mechanistic framework for the long-standing paradox that the majority of cancers are aneuploid, whereas ...

Researchers from the University of Tennessee Health Science Center have made a foundational discovery about chromosome biology through their work on the first-ever human pangenome reference. Published ...

In a biological first, an international team has inserted a man-made chromosome into brewer's yeast, producing a life form that thrives and successfully passes the designer genes on to its offspring.

Chromothripsis is a phenomenon by which tens to thousands of chromosomal rearrangements occur, with the available evidence indicating that chromothripsis can be generated by a single catastrophic ...

Highly challenging to sequence and long overlooked, the human Y chromosome's contributions to health and disease remain largely unknown. A new paper that presents, for the first time, the complete ...

A chromosome is a DNA molecule that contains genetic material. Sex chromosomes are chromosomes that affect your sexual anatomy and reproductive development. Most of us were raised with the idea that ...