Structures long blamed for blocking genes actually help them turn on, according to the Cornell Chronicle. Cornell scientists found that nucleosomes — the spools that package DNA — relieve twisting ...
It's a common storytelling trope: the stubborn foe who is eventually revealed to be a much-needed friend. Biology has its own ...
Northwestern Medicine scientists have discovered how molecular "traffic controllers" in cells influence aging and cellular ...
Gene expression is linked to RNA transcription, which cannot happen without RNA polymerase. However, this is where the similarities between prokaryote and eukaryote expression end. Central to the ...
Enzymes called RNA polymerases transcribe DNA into RNA. RNA is the intermediary that carries the information contained within DNA to the ribosomes, where the genetic information is synthesized into ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, No. 3 (January 18, 2022), pp. 1-7 (7 pages) Elongating RNA polymerase II (Pol II) can be paused or arrested ...
DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes. Among them, DNA–histone ...
A rapid isothermal amplification technique enables pathogen identification and antibiotic resistance detection in low-resource settings. Recombinase polymerase amplification (RPA) is a technique for ...
Rpb1, the largest subunit of RNA polymerase II (RNAPII), is rapidly polyubiquitinated and degraded in response to DNA damage; this process is considered to be a “mechanism of last resort” employed by ...
When TV shows like CSI: Crime Scene Investigation portray DNA processing in the forensic lab, the results appear instantly with a DNA match wrapping up the case in hours. However, the ...
DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes.
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