In 1869, Swiss scientist Friedrich Miescher isolated a mysterious substance from cell nuclei—an overlooked finding that would ...

Over the past two decades, researchers have learned that DNA inside the cell nucleus naturally folds into a network of ...

Although DNA is tightly packed and protected within the cell nucleus, it is constantly threatened by damage from normal ...

Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells. However, to be effective, the new gene must make it into a cell's nucleus. The ...

A new study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers found that the most ...

If severe DNA damage is not repaired, the consequences for the health of cells and tissues are dramatic. A study led by ...

Researchers have found that the way DNA is packaged in cells can directly impact how fast DNA itself is copied during cell division. They discovered that DNA packaging sends signals through an unusual ...

For almost 60 years, scientists have tried to understand why DNA doesn't replicate wildly and uncontrollably every time a ...

As people age, their immune systems deteriorate. This makes them more susceptible to infections and can mean that vaccines ...