The activity of alcohol dehydrogenase, an enzyme present principally in liver tissue, was repetitively determined in the serums of 266 patients with hepatic and nonhepatic diseases. The enzyme was ...

Epilepsy is a highly prevalent neurologic condition that is characterized by spontaneous recurrent seizures and occurs at all ages in approximately 1% of the world’s population. Although antiseizure ...

Mutations in isocitrate dehydrogenase (IDH) genes, an early step in the ontogeny of lower-grade gliomas, induce global epigenetic changes characterized by a hypermethylation phenotype and are critical ...

Indications: Pyruvate dehydrogenase complex deficiency, typically associated with post-prandial lactic acidemia with a normal lactate/pyruvate ratio, can be assayed in freshly isolated blood ...

Tumor-infiltrating lymphocytes (TILs) dynamics in breast cancer patients receiving neoadjuvant therapy: A systematic review and meta-analysis. Neoadjuvant pegylated liposomal doxorubicin (PLD) plus ...

Mitophagy is a selective form of autophagy via which the damaged mitochondria are cleared via the autophagy-lysosome pathway. Mitophagy is an essential part of mitochondrial quality control and plays ...

The citric acid cycle, also called the TCA or Krebs cycle, is a core metabolic pathway and a high-yield MCAT topic. It converts acetyl-CoA into ATP, NADH, and FADH2 through a sequence of enzyme-driven ...