A hallmark of Parkinson's disease is the buildup of Lewy bodies—misfolded clumps of the protein known as alpha-synuclein.

Researchers have elucidated key steps in the ubiquitin tagging of the mutated huntingtin protein, providing hope for future ...

Life runs on instructions you never see. Every cell reads DNA, turns that message into RNA, and then builds proteins that ...

An international study co-led by researchers from the University of Massachusetts Amherst and Helmholtz Munich in Germany has ...

All life on Earth shares a common ancestor that lived roughly four billion years ago. This so-called "last universal common ...

Scientists at the Yong Loo Lin School of Medicine, (NUS Medicine), have identified a molecular switch that helps aging brains ...

Researchers found that paired pathogenic variants can restore protein function rather than make it worse. This phenomenon ...

Despite its strong influence, APOE is not the sole cause of Alzheimer’s or other dementias. Even among people with the ...

Scientists have uncovered a surprising genetic shift that may explain how animals with backbones—from fish and frogs to ...

Researchers at the School of Biological Sciences of The University of Hong Kong (HKU) have uncovered how eukaryotic cells can ...