Researchers have determined whether a specific chemical modification of a protein that packages the genome called a histone affects gene activity and cell proliferation. Researchers have determined ...

Before a newly synthesized protein can undergo folding, it must be processed and transported to the correct location within the cell after emerging from the ribosome. N-terminal acetylation ...

Histone modification is an epigenetic mechanism that regulates gene expression by altering chromatin structure and DNA accessibility for transcription. Histone modification is regulated by various ...

The immune system exhibits remarkable plasticity, enabling dynamic responses to environmental cues while maintaining tissue homeostasis. Emerging evidence ...

The data showed elevated levels of the metabolite αKG improved DNA repair, and blocking it made the cancer cells more sensitive to treatment.

Every cell type in the human body carries the same approximately 3.2 billion base pairs of DNA, yet a liver cell behaves nothing like a neuron. The epigenome explains this difference: in each cell, ...

For all its mysteries, cancer can be boiled down to a disease caused by cell division gone haywire. But what determines the rate at which cancer cells can grow? They need cell building materials—amino ...