A collaborative research team has successfully developed designer enzymes that exhibit both intrinsic and extrinsic functions by transplanting a synthetic trinuclear zinc center into a human cytokine.

Osteoarthritis (OA) is a common and a complex chronic disease, characterized by pain and functional disability 1. Hand osteoarthritis (HOA) is the most common form of OA. Its incidence is directly ...

Structural equivalence is demonstrated through the comparison of a synthetic multinuclear metal complex (left) versus the designer enzyme in this report (right). A collaborative research team led by ...