Aging is an important risk factor for type 2 diabetes (T2D) 1,2 and the increasing age of the world’s populations contributes to the rapidly growing prevalence of T2D. Elderly people often exhibit ...

Researchers at the University of Twente and other Dutch knowledge institutes have developed a membrane with which individual islets of Langerhans – insulin-producing cell clusters – can be ...

We report on a patient with type 1 diabetes mellitus, diagnosed at 16 years of age, in whom widespread amyloid deposits developed many years later in transplanted human islets. The islets were ...

Detailed characterization of human pancreatic islets is key to elucidate the pathophysiology of all forms of diabetes mellitus, including its most common form known as type 2 diabetes (T2D). However, ...

CHICAGO — Ten people with type 1 diabetes, who had recurrent severe hypoglycemia and hypoglycemic unawareness, have remained insulin-independent for over a year following allogeneic stem cell-derived ...

The currently approved islet-transplant method infuses islets into a vein in the liver. This invasive procedure requires the long-term use of immune-suppressing drugs to prevent islet rejection, ...

Wenzhou Medical University researchers have reimagined the spleen as a viable site for islet transplantation, enabling long-term diabetes control without the burden of full immunosuppression.