(whoismargot/pixabay) Major depressive disorder (MDD) is a severe, clinical type of depression, a more broadly defined mood ...

Illustration of the vagus nerve. (Sebastian Kaulitzki/Science Photo Library/Getty Images) Depression affects more than 300 ...

D-serine as an adjunctive treatment did not outperform placebo overall in patients with major depressive disorder (MDD), a new trial showed. However, depressive symptoms and anhedonia were ...

A single dose of psychedelics significantly reduced symptoms in people with major depressive disorder, a new study found. The clinical trial was led by researchers at Imperial College London, where ...

Researchers found that 8.3% of US adults had at least one major depressive episode. In adolescents, the rate was 20.1%, with 29.2% of female adolescents reporting a major depressive episode. Major ...

Adding atypical antipsychotics to antidepressants for major depression offered an uneven trade-off — while some medications were better at easing symptoms, others were easier for patients to tolerate.

Lumateperone is approved as an adjunctive treatment for MDD, expanding its indications beyond schizophrenia and bipolar depression. Clinical trials showed significant symptom improvement and potential ...

A controlled clinical trial suggests a fast-acting psychedelic approach may reduce depressive symptoms, but researchers stress careful interpretation and the need for larger long-term studies. Study: ...

Depression is a common mood disorder. It is completely normal for most people to feel sad or depressed at times as a reaction to loss or life’s challenges. But when depression leads to things like ...