A protein thought to play a supporting role in DNA replication actually facilitates the whole process

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...
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Computational Model Uses Language Theory to Predict DNA Shapes That Underlie Gene Expression and Disease

R-loops are structures that form when a strand of RNA (red) forms a stable structure with double-stranded DNA, causing one strand of the DNA to form a loop. R-loops are associated with gene ...

Cells' built-in capacity limit for copying DNA could impact cancer treatment

For almost 60 years, scientists have tried to understand why DNA doesn't replicate wildly and uncontrollably every time a ...

Data-driven 3D chromosome model reveals structural and dynamic features of DNA

Chromosomes are masters of organization. These long strings of DNA fold down into an ensemble of compact structures that keep needed parts of the genome accessible while tucking away those that aren't ...