Study results indicate that mutation strength may shape both tumor–immune system interactions and immunotherapy response.

Researchers have created the first complete map showing how hundreds of mutations in a key cancer gene affect tumor growth.

Scientists have created a complete map showing how hundreds of possible mutations in a key cancer gene influence tumor growth ...

In mantle cell lymphoma (MCL), an aggressive form of B-cell non-Hodgkin lymphoma, TP53 mutations are known to affect patients’ prognosis—but questions remain. What does the heterogeneity of TP53 ...

Congenital stationary night blindness (CSNB) is caused by mutations in a specific calcium channel. A comprehensive proteomic study by researchers at the University of Innsbruck now reveals how these ...

Genetic disorders can occur due to mutations in one gene (monogenic), multiple genes (multifactorial inheritance), and mutation in one or more chromosomes. Point mutations are where one nucleotide in ...

Characteristics of Clonal Hematopoiesis (CH) Mutations - a) We identified somatic mutations in known clonal hematopoiesis of indeterminate potential (CHIP) driver genes using peripheral blood ...

Scientists have created a complete map showing how hundreds of possible mutations in a key cancer gene influence tumour growth.