Inside the brain is a dense network of neurons that receive, process, and relay information. The synapse, where neurons meet, ...
Protein tyrosine phosphatases constitute a family of enzymes that remove phosphate groups from tyrosine residues on key signalling proteins, thus acting in opposition to protein tyrosine kinases.
How do we think, feel, remember, or move? It all depends on transmission of chemical signals in the brain, carried and released by molecular containers called vesicles. In a new study, researchers ...
The mechanisms underlying the pathogenesis of epilepsy, a neurological disorder characterized by excessive electrical activity in the brain, remain unknown. Now, using a novel radiotracer ([11 C]K-2, ...
This original animation illustrates that presynaptic neurons secrete VLK, which then phosphorylates the extracellular side of ephrin type-B receptor 2 (EphB2) extruding from the membranes of ...
Two poster presentations at ACNP highlight new research on the fundamental biology of molecules targeting synaptic function in CNS disease Insights advance translational model supporting Gate’s lead ...
A protein that appears in postsynaptic protein agglomerations has been found to be crucial to their formation. The Kobe University discovery identifies a new key player for synaptic function and sheds ...
Research led by SUNY Downstate Medical Center has identified a brain receptor that appears to initiate adolescent synaptic pruning, a process believed necessary for learning, but one that appears to ...
Insights from advanced imaging technology show how neurons communicate at the atomic level for the first time. For the first time, scientists at The Hospital for Sick Children (SickKids) used advanced ...
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