Researchers analyzed 44 Bundibugyo virus genomes and modeled how approved and experimental Ebola antibodies might bind the ...

This article explores how advances in antibody engineering are moving immunotherapy beyond traditional monoclonal antibodies to bispecific and trispecific formats and logic-gated designs.

Cell surface protein labeling supports precise characterization of immune checkpoints, receptors, and other therapeutic ...

TMEM63B, a mechanosensitive lipid scramblase, has an autoinhibitory domain in its C-terminal tail that helps keep it inactive ...

Cancer antigens targeted by drug conjugates are restricted to the few membrane receptors (such as HER2 and TROP2) that ...

Respiratory syncytial virus, or RSV, remains one of the most consequential respiratory pathogens of early childhood, and the arrival of long-acting monoclonal antibody prophylaxis has transformed the ...

More adults with chronic spontaneous urticaria receiving CUE-221, a humanized anti-IgE IgG1 monoclonal antibody, achieved complete resolution of hives vs. placebo on drug and 12 weeks off drug, ...

A study has found that the immune antibody IgA, which helps protect the intestinal mucosa against bacteria and viruses, can ...

An autoinhibitory domain in the C-terminal tail of the TMEM63B, a mechanosensitive lipid scramblase, helps maintain its inactive state under resting ...

Summit and AstraZeneca have entered into an agreement whereby AstraZeneca will make an equity investment of $2.0 billion in convertible preferred shares. At the conversion ratio, the investment ...

Pregnancy demands one of the most remarkable immunological balancing acts in human biology. The developing fetus carries genetic material from both parents, making it, from the immune system’s p ...