Over the past two decades, researchers have learned that DNA inside the cell nucleus naturally folds into a network of ...
Chromosomes are masters of organization. These long strings of DNA fold down into an ensemble of compact structures that keep needed parts of the genome accessible while tucking away those that aren't ...
Three major evolutionary forces that shape prokaryote genomes include the gradual accumulation of mutations, the acquisition of genes through horizontal gene transfer, and, to a lesser extent, gene ...
Scientists at St. Jude Children's Research Hospital and Northwestern University identified a previously unknown treatment opportunity for sickle cell disease and β-thalassemia. The discovery, ...
Introduction: Following infarction, heart often undergoes pathological remodeling and dysregulation of sodium and calcium homeostasis, predisposing patients to heart failure and arrhythmias. While ...
ABSTRACT: Background: Multidrug-resistant Enterobacteriaceae pose a significant global health burden. These bacteria produce extended-spectrum beta-lactamase (ESBL) enzymes, which render them ...
ABSTRACT: Background: Liddle syndrome (LS) is a rare autosomal-dominant cause of early-life hypertension. It is associated with hypokalemic metabolic alkalosis, hyporeninemia, and suppressed ...
New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...
This study is led by Dr. Yue Zhou (State Key Laboratory of Gene Function and Modulation Research, School of Advanced Agricultural Sciences, Peking-Tsinghua Center for Life Sciences, Peking University, ...