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Low cortisol, also known as hypocortisolism or adrenal insufficiency, occurs when the adrenal glands fail to produce sufficient amounts of the hormone cortisol, leading to a condition where the body cannot effectively manage stress, maintain normal blood pressure, or regulate energy metabolism. This deficiency, which can be caused by damage to the adrenal glands (Addison's disease) or issues with the pituitary gland, often results in symptoms such as chronic fatigue, muscle weakness, unexplained
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Low cortisol, medically referred to as hypocortisolemia, is a physiological state characterized by an abnormally reduced concentration of the glucocorticoid hormone cortisol in the bloodstream relative to the levels required for normal metabolic, cardiovascular, neurological, and immune system function. Cortisol is a steroid hormone synthesized and secreted by the zona fasciculata of the adrenal cortex under regulation of the hypothalamic–pituitary–adrenal (HPA) axis. Its production is stimulate
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